Novel genetic experiment shrinks tough-to-treat cancer

In a novel experiment, a woman with advanced pancreatic cancer saw her tumors dramatically shrink after researchers in Oregon turbocharged her own immune cells. It’s not a cure. But the research highlights a possible new way to someday harness the immune system to better fight hard-to-treat cancers. Researchers culled T cells from the woman’s blood and genetically engineered them to spot a mutant protein fueling her cancer. The approach failed in a second patient but researchers have begun a small study to more closely test it. The research was published Wednesday by the New England Journal of Medicine.