ROME (AP) — Curfews, quarantines and even border closings have complicated Christmas celebrations for countless people around the globe, but ingenuity, determination and imagination helped keep the day special for many. In South Africa, a scientist spent the holiday hunkered down in his lab, sequencing the coronavirus. Newlyweds in Bangkok, quarantined in a hotel, had a Christmas tree delivered to their room. But in Colombia, border closures meant many migrants from Venezuela couldn’t go home to see families for Christmas as they have in the past. In his Christmas Day message, Pope Francis appealed to world leaders to make sure the most vulnerable and needy are first in line to get coronavirus vaccines.